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CD7 molecular target information overview


  • Molecular name: CD7, CD7 molecule
  • Gene family: CD molecules; V-set domain containing
  • Alias: GP40; LEU-9; TP41; Tp40
  • Alias: p41 protein; T-cell antigen CD7; T-cell leukemia antigen; CD7 antigen (p41)


    • CD7 molecular target review


    The 4H9 monoclonal antibody specifically binds to human CD7, a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on the surface of T cells, NK cells, and acute lymphoblastic leukemia cells. CD7 is involved in regulating cytokine secretion and cell adhesion. It is able to provide co-stimulatory signals and associates with CD3 and CD45, and CD7 is involved in T cell activation.


    Human CD7 Molecular Target Information


    Molecular name: CD7, CD7 molecule


    Alias:

    • CD7 antigen (p41)
    • GP40
    • LEU-9
    • p41 protein
    • T-cell antigen CD7
    • T-cell leukemia antigen
    • T-cell surface antigen Leu-9
    • Tp40
    • TP41

    Gene sequence:NCBI_Gene: 924

    Protein sequence:UniProtKB: P09564


    Human CD7 target molecule function (prediction)


    Predicted to enable signaling receptor activity. Predicted to be involved in T cell activation and immune response. Predicted to act upstream of or within homeostasis of number of cells within a tissue. Predicted to be located in plasma membrane. Predicted to be integral component of membrane.


    Mouse Cd7 molecular target information


    Molecular name: Cd7, CD7 antigen


    Alias:

    • None


    Gene sequence:NCBI_Gene: 12516

    Protein sequence:


    Mouse Mouse Cd7 target molecular function (prediction)


    Predicted to enable signaling receptor activity. Acts upstream of or within homeostasis of number of cells within a tissue. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; hemolymphoid system gland; intestine; liver and biliary system; and reproductive system. Orthologous to human CD7 (CD7 molecule).


    Rat Cd7 molecular target information


    Molecular name: Cd7, Cd7 molecule

    Alias:

    • CD7 antigen
    • LOC303747
    • T-cell antigen CD7

    Gene sequence:NCBI_Gene: 303747

    Protein sequence:UniProtKB: B2RZ54


    Rat Cd7 target molecular function (prediction)


    Predicted to enable signaling receptor activity. Predicted to be involved in adaptive immune response. Predicted to act upstream of or within homeostasis of number of cells within a tissue. Predicted to be integral component of membrane. Orthologous to human CD7 (CD7 molecule).