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CD5 molecular target information overview


  • Molecular name: CD5, CD5 molecule
  • Gene family: CD molecules; Scavenger receptor cysteine rich domain containing
  • Alias: T1
  • Former name: LEU1
  • Alias: CD5 antigen (p56-62)


    • CD5 molecular target review


    The CD5 molecule is a glycoprotein with a molecular weight of 67 kD. It consists of an extracellular region of 347 amino acids and an intracellular region of 93 amino acids. It belongs to a cysteine-rich scavenger receptor family. It is expressed in mature T cells and a small number of normal B cells. CD5 antigen-positive T lymphocytes have signal transduction functions, while CD5 antigen-positive B lymphocytes, in addition to their immune functions, are also closely related to the occurrence of diseases.


    Human CD5 Molecular Target Information


    Molecular name: CD5, CD5 molecule


    Alias:

    • cd5 antigen
    • CD5 antigen (p56-62)
    • LEU1
    • lymphocyte antigen T1/Leu-1
    • T-cell surface glycoprotein CD5
    • T1

    Gene sequence:NCBI_Gene: 921

    Protein sequence:UniProtKB: P06127


    Human CD5 target molecule function (prediction)


    Predicted to enable scavenger receptor activity. Predicted to be involved in T cell costimulation. Predicted to act upstream of or within apoptotic signaling pathway. Located in plasma membrane.


    Mouse Mouse Cd5 molecular target information


    Molecular name: Cd5, CD5 antigen


    Alias:

    • Ly-1
    • Ly-12
    • Ly-A
    • lymphocyte antigen 1
    • lymphocyte antigen 12
    • Lyt-1
    • T-lymphocyte antigen 1


    Gene sequence:NCBI_Gene: 12507

    Protein sequence:


    Mouse Mouse Cd5 target molecular function (prediction)


    Predicted to enable scavenger receptor activity. Acts upstream of or within T cell costimulation and apoptotic signaling pathway. Located in external side of plasma membrane. Is expressed in gut and male reproductive gland or organ. Orthologous to human CD5 (CD5 molecule).


    Rat Cd5 molecular target information


    Molecular name: Cd5, Cd5 molecule

    Alias:

    • CD5 antigen
    • LOC100911215
    • lymphocyte antigen CD5
    • MGC114334
    • T-cell surface glycoprotein CD5
    • T-cell surface glycoprotein CD5-like

    Gene sequence:NCBI_Gene: 54236

    Protein sequence:


    Rat Cd5 target molecular function (prediction)


    Predicted to enable scavenger receptor activity. Predicted to be involved in T cell costimulation. Predicted to act upstream of or within apoptotic signaling pathway. Is spanning component of plasma membrane. Orthologous to human CD5 (CD5 molecule).