GDF-8 Rabbit Polyclonal Antibody

GDF-8 Rabbit Polyclonal Antibody

Size1:50μl Price1:$128
Size2:100μl Price2:$230
Size3:500μl Price3:$980 SKU: APRab11388 Category: Polyclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

GDF-8 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

IHC,ELISA

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

MSTN

Alternative Names

MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin

Gene ID

2660

SwissProt ID

O14793

 

Application

Dilution Ratio

IHC 1:100-1:300 ELISA: 1:10000

Molecular Weight

 

Background

myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],function:Acts specifically as a negative regulator of skeletal muscle growth.,online information:Myostatin entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity.,

 

Research Area

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