Recombinant Human Tie-1 (C-6His)

Recombinant Human Tie-1 (C-6His)

Size1:10μg price1:$66
Size2:50μg price2:$186
Size3:500μg price3:$930 SKU: PHH1754 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human Tie-1 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Tyrosine Kinase With Immunoglobulin And Epidermal Growth Factor Homology Domains 1 is produced by our Mammalian expression system and the target gene encoding Ala22-Gln760 is expressed with a 6His tag at the C-terminus.

Accession #

P35590

Host

Human Cells

Species

Human

Predicted Molecular Mass

81 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 10% Sucrose, pH8.2.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Tyrosine-Protein Kinase Receptor Tie-1; TIE1; TIE

 

Background

TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2, but no ligand was found for TIE-1.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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