Recombinant Human CSNK1G2 (N-6His)

Recombinant Human CSNK1G2 (N-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890 SKU: PEH0235 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human CSNK1G2 (N-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Casein kinase I Isoform Gamma-2 is produced by our E.coli expression system and the target gene encoding Met1-Lys415 is expressed with a 6His tag at the N-terminus.

Accession #

P78368

Host

E.coli

Species

Human

Predicted Molecular Mass

47.6 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 10% Glycerol, 1mM DTT, pH 8.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Casein kinase I isoform gamma-2; CK1G2; CSNK1G2

 

Background

CSNK1G2 is a cytoplasmic protein which contains one protein kinase domain. It is amember of the CK1 Ser/Thr protein kinase family of the large casein kinase I (CKI) subfamily. CSNK1G2 participates in Wnt signaling, involves in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. It regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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