CDT2 Rabbit Monoclonal Antibody

CDT2 Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe01814 Category: Rabbit Monoclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

CDT2 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

DTL

Alternative Names

CDW1; DCAF2; Dtl; L2DTL; RAMP

Gene ID

51514

SwissProt ID

Q9NZJ0

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 79 kDa; Observed MW: 79 kDa

 

Background

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).

 

Research Area

Cell Biology

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