Summary
Performance
Immunogen
Application
Background
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Research Area
Epigenetics and Nuclear Signaling
Summary
Production Name | KMT4 Rabbit Monoclonal Antibody |
Description | Recombinant Rabbit Monoclonal antibody |
Host | Rabbit |
Application | WB,IHC |
Reactivity | Human,Mouse |
Performance
Conjugation | Unconjugated |
Modification | Unmodified |
Isotype | IgG |
Clonality | Monoclonal Antibody |
Form | Liquid |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Purification | Affinity Purified |
Immunogen
Gene Name | DOT1L |
Alternative Names | DOT 1; DOT1L; KMT4; Histone methyltransferase DOT1L; H3 lysine-79 specific |
Gene ID | 84444 |
SwissProt ID | Q8TEK3 |
Application
Dilution Ratio | WB: 1/500-1/1000 IHC: 1/50-1/100 |
Molecular Weight | Calculated MW: 165 kDa; Observed MW: 185 kDa |
Background
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Research Area
Epigenetics and Nuclear Signaling