Recombinant Mouse ST6GalNAc2 (C-6His)

Recombinant Mouse ST6GalNAc2 (C-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890
SKU: PHM1564 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Mouse ST6GalNAc2 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus.

Accession #

P70277

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

40.4 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 50mMTris-HCl, 150mM NaCl, pH 7.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase,GalNAc alpha-2,6-sialyltransferase II,ST6GalNAc II,Sialyltransferase 7B,SIAT7-B

 

Background

Alpha‑N‑acetylgalactosaminide alpha ‑2,6‑sialyltransferase 2, is a type/xa0II membrane protein localized in the Golgi network and catalyzes 2,6‑sialylation of the Tn antigen. Sialyl‑Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis./xa0it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.

 

Note

For Research Use Only , Not for Diagnostic Use.