MDR1 Rabbit Monoclonal Antibody

MDR1 Rabbit Monoclonal Antibody

Size1:50μL Price1:$138
Size2:100μL Price2:$240
Size3:200μL Price3:$380
Application:WB,IHC,IF,IP,ELISA
Reactivity:Human,
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:ABCB1 MDR1 PGY1 SKU: AMRe21283 Category: Rabbit Monoclonal Antibody Tags: , , , , , , ,

Datasheet

Summary

Production Name

MDR1 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC,IF,IP,ELISA

Reactivity

Human,

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG,Kappa

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Purification

Protein A

 

Immunogen

Gene Name

ABCB1 MDR1 PGY1

Alternative Names

ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1

Gene ID

5243

SwissProt ID

P08183

 

Application

Dilution Ratio

IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;

Molecular Weight

Calculated MW:141kD;Observed MW:141kD

 

Background

Cell localization:Membrane.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008],

 

Research Area

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