RAP80 Rabbit Polyclonal Antibody($99/20μL)

RAP80 Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB,IHC-P,ICC/IF
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:UIMC1 SKU: APRab00256 Category: Polyclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

RAP80 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

UIMC1

Alternative Names

RAP80; X2HRIP110

Gene ID

51720

SwissProt ID

Q96RL1

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200

Molecular Weight

Calculated MW: 80 kDa; Observed MW: 80 kDa

 

Background

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).

 

Research Area

Epigenetics and Nuclear Signaling

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