RBAK Rabbit Polyclonal Antibody($99/20μL)

RBAK Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$128
Size3:100μL Price2:$230
Size4:200μL Price3:$380
Application:WB,IF-P,IF-F,ICC/IF,ELISA,IHC-P
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:RBAK SKU: APRab16942 Category: Polyclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

RBAK Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IF-P,IF-F,ICC/IF,ELISA,IHC-P

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

RBAK

Alternative Names

RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769

Gene ID

57786

SwissProt ID

Q9NYW8

 

Application

Dilution Ratio

WB 1:500-2000, IF-P/IF-F/ICC/IF/ICC 1:50-200, ELISA 1:2000-20000, IHC-P 1:50-200

Molecular Weight

85kDa

 

Background

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011],function:May repress E2F-dependent transcription. May promote AR-dependent transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 16 C2H2-type zinc fingers.,subunit:Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR.,tissue specificity:Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.,

 

Research Area

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