Raf1 Rabbit Polyclonal Antibody($99/20μL)

Raf1 Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB,IHC-P,ELISA
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:RAF1 SKU: APRab00545 Category: Polyclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

Raf1 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

RAF1

Alternative Names

RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1

Gene ID

5894

SwissProt ID

P04049

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 ELISA: 1:10000

Molecular Weight

Calculated MW: 73 kDa; Observed MW: 73 kDa

 

Background

Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.

 

Research Area

Signal Transduction

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