Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody

Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody

Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IP
Reactivity:Human,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:AKT1 SKU: AMRe02836 Category: Rabbit Monoclonal Antibody Tags: , , , , , , ,

Datasheet

Summary

Production Name

Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Human,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purification

 

Immunogen

Gene Name

AKT1

Alternative Names

AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha

Gene ID

207

SwissProt ID

P31749

 

Application

Dilution Ratio

WB: 1:500-1:1000  IP: 1:20

Molecular Weight

Calculated MW: 56 kDa; Observed MW: 56 kDa

 

Background

Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

 

Research Area

Neuroscience

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