DAPK2 Rabbit Monoclonal Antibody

DAPK2 Rabbit Monoclonal Antibody

Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,IHC-P
Reactivity:Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:DAPK2 SKU: AMRe01894 Category: Recombinant Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

DAPK2 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-P

Reactivity

Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

DAPK2

Alternative Names

DAPK2; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1

Gene ID

23604

SwissProt ID

Q9UIK4

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100

Molecular Weight

Calculated MW: 43 kDa; Observed MW: 43 kDa

 

Background

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).

 

Research Area

Cell Biology

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