Summary
Performance
Immunogen
Application
Background
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area
Signal Transduction; Protein Trafficking; Golgi Proteins; Cancer; Signal transduction; Autophagy; Metabolism; Pathways and Processes; Metabolism processes; Autophagy and mitophagy; Signal Transduction; Neuroscience