Summary
Performance
Immunogen
Application
Background
Plays an important role in the regulation of apoptosis in various physiological systems. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Research Area
Summary
Production Name | TNFRSF10B Mouse Monoclonal Antibody |
Description | Mouse Monoclonal Antibody |
Host | Mouse |
Application | WB |
Reactivity | Human |
Performance
Conjugation | Unconjugated |
Modification | Unmodified |
Isotype | Mouse IgG2b |
Clonality | Monoclonal Antibody |
Form | Liquid |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer | Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol. |
Purification | Affinity Purification |
Immunogen
Gene Name | TNFRSF10B |
Alternative Names | Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; Fas like protein precursor; KILLER; KILLER/DR5; OTTHUMP00000123492; OTTHUMP00000123493; p53 regulated DNA damage inducible cell death receptor (killer); p53 regulated DNA damage inducible cell death receptor(killer); TNF related apoptosis inducing ligand receptor 2; TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TR10B_HUMAN; TRAIL R2; TRAIL receptor 2; TRAIL-R2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; Tumor necrosis factor receptor superfamily; member 10b; ZTNFR9. |
Gene ID | 8795 |
SwissProt ID | O14763 |
Application
Dilution Ratio | WB:1:500-1:1000 |
Molecular Weight | Calculated MW: 48 kDa; Observed MW: 40,48 kDa |
Background
Plays an important role in the regulation of apoptosis in various physiological systems. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Research Area