KDM1A Rabbit Monoclonal Antibody

KDM1A Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Application:WB,IP,ICC
Reactivity:Human,Rat,Hamster
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:KDM1A SKU: AMRe85732 Category: Recombinant Monoclonal Antibody Tags: , , , , , , ,

Summary

Production Name

KDM1A Rabbit Monoclonal Antibody Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IP,ICC

Reactivity

Human,Rat,Hamster

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

KDM1A

Alternative Names

KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

Gene ID

23028

SwissProt ID

O60341

 

Application

Dilution Ratio

WB:1:500-1:1000,IP:45677,ICC:1:50-1:200

Molecular Weight

Calculated MW: 93 kDa; Observed MW: 110 kDa

 

Background

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

 

Research Area

Epigenetics and Nuclear Signaling

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