MEK7 Rabbit Monoclonal Antibody

MEK7 Rabbit Monoclonal Antibody

SKU: AMRe03944 ★ ★ ★ ★ ★
Size1:50μL Price1:$158
Size2:100μL Price2:$288
Size3:200μL Price3:$520
Application:WB,IHC-F,IHC-P,FC
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MAP2K7 Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

MEK7 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,FC

Reactivity

Human, Mouse, Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% protective protein .

Purification

Affinity Purification

 

Immunogen

Gene Name

MAP2K7

Alternative Names

MAP2K7; JNKK2; MEK7; MKK7; PRKMK7; SKK4; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; S

Gene ID

5609

SwissProt ID

O14733

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 FC: 1:50-1:100

Molecular Weight

Calculated MW:48 kDa;Observed MW: 48 kDa

 

Background

MKK7 is strongly activated by TNF-α, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-α. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.

 

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