PBR Rabbit Polyclonal Antibody($99/20μL)

PBR Rabbit Polyclonal Antibody($99/20μL)

SKU: APRab00036 ★ ★ ★ ★ ★
Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB,IHC-P,ICC/IF,FC,IP
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TSPO Category: Polyclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

PBR Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,ICC/IF,FC,IP

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

TSPO

Alternative Names

TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR

Gene ID

706

SwissProt ID

P30536

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100

Molecular Weight

Calculated MW: 19 kDa; Observed MW: 19 kDa

 

Background

Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation. A cytoplasmic protein, PRAX-1 （peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.

 

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