IRS1 (17G5) Rabbit Monoclonal Antibody

IRS1 (17G5) Rabbit Monoclonal Antibody

Cat: AMRe12758
Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:IRS1 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

IRS1 (17G5) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,FC

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

IRS1

Alternative Names

HIRS1; Insulin receptor substrate 1; IRS 1; IRS1;

Gene ID

3667

SwissProt ID

P35568

 

Application

Dilution Ratio

WB 1:1000-1:5000,IHC 1:20-1:50,ICC/IF 1:50-1:200,FC 1:20-1:50

Molecular Weight

132kDa

 

Background

IRS1 is one of the major substrates of the insulin receptor kinase. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

 

Research Area

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