S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

Cat: AMRe17461
Size1:50μL Price1:$138
Size2:100μL Price2:$240
Size3:200μL Price3:$380
Application:WB,IHC-P,ICC/IF,IF-P
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:S100A6 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,IHC-P,ICC/IF,IF-P

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

S100A6

Alternative Names

Protein S100-A6; Calcyclin; MLN 4; PRA; CACY; CABP; 5B10;

Gene ID

6277

SwissProt ID

P06703

 

Application

Dilution Ratio

WB 1:1000, IHC-P/IF-P 1:50, ICC/IF 1:200-1:500

Molecular Weight

10kDa

 

Background

S100A6 (calcyclin) is involved in a number of cellular processes, including exocytosis and cell cycle regulation. In addition, S100A6 interacts with a number of proteins such as SIP, GAPDH, and annexins in a calcium-dependent fashion. Research studies demonstrate that a down regulation of corresponding S100A6 gene expression causes a decrease in cell proliferation. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

 

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