PDPK1 Mouse Monoclonal Antibody-EnkiLife

PDPK1 Mouse Monoclonal Antibody

Summary

Production Name	PDPK1 Mouse Monoclonal Antibody
Description	Mouse monoclonal Antibody
Host	Mouse
Application	WB,IHC,ICC,ELISA,FC
Reactivity	Human,Mouse,Monkey,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Mouse IgG1
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in PBS with 0.05% sodium azide
Purification	Affinity Purification

Immunogen

Gene Name	PDPK1
Alternative Names	PDK1; PDPK2; PDPK2P; PRO0461
Gene ID	5170
SwissProt ID	O15530

Application

Dilution Ratio	WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight	63.2kDa

Background

Phosphoinositide-dependent kinase 1 (PDPK1, PDK1) is a serine/threonine protein kinase integral to the function of the PI 3-K/Akt signaling pathway. PDK1 and mTORC2 both phosphorylate and activate PKB/Akt, ensuring a cellular response to stimuli such as growth factors and insulin signaling. Akt is the main effector of PDK1.

Research Area

PI3K-Akt signaling pathway,mTOR signaling pathway