PARP1 Mouse Monoclonal Antibody

PARP1 Mouse Monoclonal Antibody

Cat: AMM85021
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PARP1 Category: Mouse Monoclonal Antibody Tags: , , , , , , ,

Summary

Production Name

PARP1 Mouse Monoclonal Antibody

Description

Mouse monoclonal Antibody

Host

Mouse

Application

WB,IHC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

PARP1

Alternative Names

PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Gene ID

142

SwissProt ID

P09874

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100

Molecular Weight

Calculated MW: 113 kDa; Observed MW: 116 kDa

 

Background

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

 

Research Area

Apoptosis

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