Summary
Performance
Immunogen
Application
Background
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Research Area
Cell Biology; Proteolysis / Ubiquitin; Proteasome / Ubiquitin; Ub-like Proteins; Neuroscience; Neurology process; Neurodegenerative disease; Cancer; Oncoproteins/suppressors; Tumor suppressors; Cardiovascular; Heart; Autophagy; APG gene products; Signal transduction; Metabolism; Pathways and Processes; Metabolism processes; Autophagy and mitophagy; Cell Death
