Ku80 Rabbit Monoclonal Antibody-EnkiLife

Ku80 Rabbit Monoclonal Antibody

Cat: AMRe87254

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Application:WB, IHC-P, FC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Ku80 Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IHC-P, FC, Human

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Summary

Production Name	Ku80 Rabbit Monoclonal Antibody
Description	Rabbit Monoclonal antibody
Host	Rabbit
Application	WB, IHC-P, FC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein . Stable for 12 months from date of receipt.
Purification	Affinity Purification

Immunogen

Gene Name	Ku80
Alternative Names	KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
Gene ID	7520
SwissProt ID	P13010

Application

Dilution Ratio	WB: 1:1000 IHC-P: 1:200-1:500 FC: 1:100
Molecular Weight	Calculated MW:83 kDa; Observed MW:83 kDa

Background

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Research Area

Epigenetics and Nuclear Signaling