Summary
Performance
Immunogen
Application
Background
AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Research Area
Cardiovascular; Blood; Serum Proteins; Cancer: Tumor biomarkers; Tumor antigens; Developmental; Biology; Organogenesis; Gut development; Liver development; Kits/ Lysates/ Other; Kits; ELISA Kits; Cardiovascular ELISA kits
