CD130 Rabbit Polyclonal Antibody($99/20μL)-EnkiLife

CD130 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00957

Size1:20μL Price1:$99
Size2:50μL Price1:$150
Size3:100μL Price2:$280
Size4:200μL Price3:$520
Application:WB,IHC-P
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:IL6ST Category: Polyclonal Antibody Tags: Cell Biology, Rabbit, Unconjugated, WB, IHC, Human, Mouse

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Summary

Production Name	CD130 Rabbit Polyclonal Antibody
Description	Rabbit Polyclonal Antibody
Host	Rabbit
Application	WB,IHC-P
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide.
Purification	Affinity Purification

Immunogen

Gene Name	IL6ST
Alternative Names	Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130
Gene ID	3572
SwissProt ID	P40189

Application

Dilution Ratio	WB: 1:500-1:1000 IHC: 1:50-1:100
Molecular Weight	Calculated MW: 104 kDa; Observed MW: 130-140kDa

Background

The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.