Smad5 Rabbit Polyclonal Antibody($99/20μL)-EnkiLife

Smad5 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00017

Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB,IHC-P,ICC/IF,FC
Reactivity:Human,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:SMAD5 Category: Polyclonal Antibody Tags: Signal Transduction, Rabbit, Unconjugated, WB, IHC, IF, FC, Human, Rat

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Summary

Production Name	Smad5 Rabbit Polyclonal Antibody
Description	Rabbit Polyclonal Antibody
Host	Rabbit
Application	WB,IHC-P,ICC/IF,FC
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Affinity Chromatography

Immunogen

Gene Name	SMAD5
Alternative Names	DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad 5; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD; mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; Smad5; Smad5; SMAD5_HUMAN.
Gene ID	4090
SwissProt ID	Q99717

Application

Dilution Ratio	WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 FC: 1:50-1:100
Molecular Weight	Calculated MW: 52 kDa; Observed MW: 52 kDa

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. Smad5 is a receptor-regulated Smad (R-Smad). Smad5 is required for normal development of the cardiovascular system in vivo; lack of the Smad5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of Smad5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.