Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody($99/20μL)-EnkiLife

Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00698

Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB,IHC-P,ICC/IF,IP
Reactivity:Human,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:RPS6KA5 Category: Polyclonal Antibody Tags: Signal Transduction, Rabbit, Phospho, WB, IHC, IF, IP, Human, Rat

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Summary

Production Name	Phospho-MSK1 (Ser376) Rabbit Polyclonal Antibody
Description	Rabbit Polyclonal Antibody
Host	Rabbit
Application	WB,IHC-P,ICC/IF,IP
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Affinity Chromatography

Immunogen

Gene Name	RPS6KA5
Alternative Names	RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL
Gene ID	9252
SwissProt ID	O75582

Application

Dilution Ratio	WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20
Molecular Weight	Calculated MW: 90 kDa; Observed MW: 90 kDa

Background

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.