Histone H2A.X Rabbit Monoclonal Antibody

Histone H2A.X Rabbit Monoclonal Antibody

SKU: AMRe03029 ★ ★ ★ ★ ★
Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,IHC-F,IHC-P,ICC/IF,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:H2AX Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

Histone H2A.X Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

H2AX

Alternative Names

H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X

Gene ID

3014

SwissProt ID

P16104

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20

Molecular Weight

Calculated MW: 15 kDa; Observed MW: 15 kDa

 

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

 

Research Area

Cell Biology

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