MNK2 (Phospho-Thr244) Rabbit Polyclonal Antibody($99/20μL)

MNK2 (Phospho-Thr244) Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab05808
Size1:20μL Price1:$99
Size2:50μL Price1:$128
Size3:100μL Price2:$230
Size4:200μL Price3:$380
Application:WB
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MKNK2 GPRK7 MNK2 Category: Polyclonal Antibody Tags:

Summary

Production Name

MNK2 (Phospho-Thr244) Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

MKNK2

Alternative Names

MAP kinase-interacting serine/threonine-protein kinase 2(MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)

Gene ID

2872

SwissProt ID

Q9HBH9

 

Application

Dilution Ratio

WB 1:500-2000

Molecular Weight

51kDa

 

Background

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Binds 1 zinc ion per subunit.,cofactor:Magnesium.,function:May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.,PTM:Dual phosphorylation of Thr-244 and Thr-249 activates the kinase. Phosphorylation of Thr-379 activates the kinase.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2. Isoform 2 interacts with ESR2.,tissue specificity:Ubiquitously expressed in all tissues examined. Isoform 2 is expressed at higher levels in the ovary than is isoform 1.,

 

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