PTEN Rabbit Polyclonal Antibody($99/20μL)

PTEN Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab01381
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280

Size:200μL Price:$520
Application:WB

Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:PTEN Category: Polyclonal Antibody Tags: , , , ,

Summary

Production Name

PTEN Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

PTEN

Alternative Names

PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Gene ID

5728

SwissProt ID

P60484

 

Application

Dilution Ratio

WB 1:500-1:1000

Molecular Weight

Calculated MW: 47 kDa; Observed MW: 54 kDa

 

Background

Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.

 

Research Area

Cell Biology

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