TRIM25 Rabbit Polyclonal Antibody($99/20μL)

TRIM25 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00268
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC,ICC/IF,FC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TRIM25 Category: Polyclonal Antibody Tags: , , , , , , , , , ,

Summary

Production Name

TRIM25 Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,FC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

TRIM25

Alternative Names

TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147

Gene ID

7706

SwissProt ID

Q14258

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 71 kDa; Observed MW: 71 kDa

 

Background

Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.

 

Research Area

Cell Biology

Related products

   💬 WhatsApp