Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody($99/20μL)

Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$168
Size3:100μL Price2:$300
Size4:200μL Price3:$520
Application:WB
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:HDAC6 SKU: APRab00938 Category: Polyclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

HDAC6

Alternative Names

HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Gene ID

10013

SwissProt ID

Q9UBN7

 

Application

Dilution Ratio

WB: 1:500-1:1000

Molecular Weight

Calculated MW: 131 kDa; Observed MW: 131 kDa

 

Background

Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.

 

Research Area

Epigenetics and Nuclear Signaling

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