Metalloproteinase Inhibitor 1 Rabbit Polyclonal Antibody($99/20μL)

Metalloproteinase Inhibitor 1 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00388
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC,ICC/IF,ELISA
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TIMP1 Category: Polyclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

Metalloproteinase Inhibitor 1 Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

TIMP1

Alternative Names

TIMP1; CLGI; TIMP; Metalloproteinase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1

Gene ID

7076

SwissProt ID

P01033

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000

Molecular Weight

Calculated MW: 23 kDa; Observed MW: 23 kDa

 

Background

TIMP1 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

 

Research Area

Cardiovascular

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