BUBR1 Rabbit Polyclonal Antibody($99/20μL)

BUBR1 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab00194
Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC,FC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:BUB1B Category: Polyclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

BUBR1 Rabbit Polyclonal Antibody

Description

Rabbit polyclonal Antibody

Host

Rabbit

Application

WB,IHC,FC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

BUB1B

Alternative Names

BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1

Gene ID

701

SwissProt ID

O60566

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 120 kDa; Observed MW: 120 kDa

 

Background

Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.

 

Research Area

Cell Biology

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