Phospholamban Rabbit Monoclonal Antibody

Phospholamban Rabbit Monoclonal Antibody

Cat: AMRe02437
Size:50μL Price:$168
Size:100μL Price:$300

Size:200μL Price:$520
Application:WB,IHC,IP

Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:PLN Category: Recombinant Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

Phospholamban Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

PLN

Alternative Names

PLN; PLB; Cardiac phospholamban; PLB

Gene ID

5350

SwissProt ID

P26678

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Molecular Weight

Calculated MW: 6 kDa; Observed MW: 12,24 kDa

 

Background

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.

 

Research Area

Signal Transduction

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