CDC7 Rabbit Monoclonal Antibody

CDC7 Rabbit Monoclonal Antibody

Cat: AMRe01804
Size:50μL Price:$158
Size:100μL Price:$288
Size:200μL Price:$520
Application:WB,IP
Reactivity:Human,Hamster
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CDC7 Category: Recombinant Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

CDC7 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Human,Hamster

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

CDC7

Alternative Names

Cell division cycle 7-related protein kinase; EC 2.7.11.1; CDC7-related kinase; HsCdc7; huCdc7; CDC7; CDC7L1; Hsk1; CDC7 kinase

Gene ID

8317

SwissProt ID

O00311

 

Application

Dilution Ratio

WB 1:500-1:1000,IP 1:20-1:50

Molecular Weight

Calculated MW: 64 kDa; Observed MW: 64 kDa

 

Background

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins).

 

Research Area

Cell Biology

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