Name: AF10 Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe85264
Price: 168 USD
Availability: InStock
Rating: 5 (1 reviews)

AF10 Rabbit Monoclonal Antibody

Cat: AMRe85264

Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:AF10 Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IHC, Human

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Summary

Production Name	AF10 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
Purification	Affinity Purification

Immunogen

Gene Name	AF10
Alternative Names	MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein
Gene ID	8028
SwissProt ID	P55197

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight	Calculated MW: 113 kDa; Observed MW: 140 kDa

Background

Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302).

Research Area