Ku70 Rabbit Monoclonal Antibody

Ku70 Rabbit Monoclonal Antibody

SKU: AMRe03060 ★ ★ ★ ★ ★
Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,IHC-P,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:XRCC6 Category: Recombinant Monoclonal Antibody Tags: , , , , , , ,

Summary

Production Name

Ku70 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-P,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

XRCC6

Alternative Names

XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-

Gene ID

2547

SwissProt ID

P12956

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IP: 1:20

Molecular Weight

Calculated MW: 70 kDa; Observed MW: 70 kDa

 

Background

It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.

 

Research Area

Related products