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LSP1 (8U19) Rabbit Monoclonal Antibody

LSP1 (8U19) Rabbit Monoclonal Antibody

Cat: AMRe13465
Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IHC,IF-P
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:LSP1 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

LSP1 (8U19) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,IF-P

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

Purification

Affinity purification

 

Immunogen

Gene Name

LSP1

Alternative Names

Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein;

Gene ID

4046

SwissProt ID

P33241

 

Application

Dilution Ratio

WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200

Molecular Weight

37kDa

 

Background

LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils. May play a role in mediating neutrophil activation and chemotaxis.

 

Research Area

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