PTEN Mouse Monoclonal Antibody

PTEN Mouse Monoclonal Antibody

Cat: AMM84951
Size:50μL Price:$168
Size:100μL Price:$300
Application:IHC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PTEN Category: Mouse Monoclonal Antibody Tags:

Summary

Production Name

PTEN Mouse Monoclonal Antibody

Description

Mouse monoclonal Antibody

Host

Mouse

Application

IHC

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

PTEN

Alternative Names

PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Gene ID

5728

SwissProt ID

P60484

 

Application

Dilution Ratio

IHC 1:50-1:100

Molecular Weight

/

 

Background

Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.

 

Research Area

Apoptosis,PI3K-Akt signaling pathway

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