Cell Biology

The NCI-H1395 cell line, as an important model of human lung adenocarcinoma, has recently made multiple advances in the pathophysiology of lung cancer research. Including screening diagnostic and metastasis markers through differential expression of extracellular vesicle microRNAs, exploring the sensitivity and chemotherapy resistance of drugs such as quercetin, discovering the amplification phenomenon of ADAR1 gene, optimizing culture conditions and improving STR identification, providing multi-faceted support for lung cancer research.

The molecular mechanisms underlying the occurrence and development of non-small cell lung cancer remain a hot and difficult topic in current research. Recent studies have shown that microRNAs play an important role in the development of tumors.

NK-92 cells originate from patients with malignant non Hodgkin lymphoma and have strong cytotoxicity. At present, clinical trial results have shown limited efficacy of NK-92 cell infusion after irradiation in patients with various hematological malignancies.