Name: 4E BP1 Rabbit Polyclonal Antibody
Brand: Enkilife Limited
SKU: APRab01368
Price: 150 USD
Availability: InStock
Rating: 5 (1 reviews)

4E BP1 Rabbit Polyclonal Antibody($99/20μL)

Cat: APRab01368

Size:20μL Price:$99
Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:WB,IHC,FC,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:EIF4EBP1 Category: Polyclonal Antibody Tags: Unconjugated, Epigenetics and Nuclear Signaling, Rabbit, WB, IHC, FC, IP, Human

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Summary

Production Name	4E BP1 Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	WB,IHC,FC,IP
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	EIF4EBP1
Alternative Names	EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Gene ID	1978
SwissProt ID	Q13541

Application

Dilution Ratio	WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight	Calculated MW: 13 kDa; Observed MW: 15-20 kDa

Background

Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.

Research Area

Epigenetics and Nuclear Signaling