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AKAP13 Mouse Monoclonal Antibody

AKAP13 Mouse Monoclonal Antibody

Cat: AMM86069
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:AKAP13 Category: Mouse Monoclonal Antibody Tags:

Summary

Production Name

AKAP13 Mouse Monoclonal Antibody

Description

Mouse monoclonal Antibody

Host

Mouse

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Purification

Affinity Purification

 

Immunogen

Gene Name

AKAP13

Alternative Names

A-kinase anchor protein 13, AKAP-13, AKAP-Lbc, Breast cancer nuclear receptor-binding auxiliary protein, Guanine nucleotide exchange factor Lbc, Human thyroid-anchoring protein 31, Lymphoid blast crisis oncogene, LBC oncogene, Non-oncogenic Rho GTPase-specific GTP exchange factor, Protein kinase A-anchoring protein 13, PRKA13, p47, AKAP13, BRX, HT31, LBC

Gene ID

11214

SwissProt ID

Q12802

 

Application

Dilution Ratio

WB 1:2000-1:8000

Molecular Weight

307.6kDa

 

Background

Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.

 

Research Area

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