Name: ALKBH5 Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe87757
Price: 168 USD
Availability: InStock

ALKBH5 Rabbit Monoclonal Antibody

Cat: AMRe87757

Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:ALKBH5 Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IHC-P, Human, Mouse, Rat

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Summary

Production Name	ALKBH5 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.
Purification	Affinity Purification

Immunogen

Gene Name	ALKBH5
Alternative Names	ABH5; OFOXD; OFOXD1
Gene ID	54890
SwissProt ID	Q6P6C2

Application

Dilution Ratio	WB 1:500-1:2000,IHC 1:200-1:2000
Molecular Weight	Calculated MW:44 kDa; Observed MW:44-48 kDa

Background

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

Research Area