BANP Mouse Monoclonal Antibody

BANP Mouse Monoclonal Antibody

Cat: AMM86023
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC

Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:BANP
Category: Mouse Monoclonal Antibody Tags:

Summary

Production Name

BANP Mouse Monoclonal Antibody

Description

Mouse monoclonal Antibody

Host

Mouse

Application

WB,IHC

Reactivity

Human, Mouse, Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Purification

Affinity Purification

 

Immunogen

Gene Name

BANP

Alternative Names

Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP, BEND1, SMAR1

Gene ID

54971

SwissProt ID

Q8N9N5

 

Application

Dilution Ratio

WB 1:500-1:2000,IHC 1:100-1:500

Molecular Weight

56.5kDa

 

Background

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

 

Research Area

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