Bad Rabbit Monoclonal Antibody

Bad Rabbit Monoclonal Antibody

Size1:50μL Price1:$158
Size2:100μL Price2:$288
Size3:200μL Price3:$520
Application:WB,IHC-F,IHC-P,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:BAD SKU: AMRe01709 Category: Rabbit Monoclonal Antibody Tags: , , , , , , , , ,

Datasheet

Summary

Production Name

Bad Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purification

 

Immunogen

Gene Name

BAD

Alternative Names

BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter

Gene ID

572

SwissProt ID

Q92934

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20

Molecular Weight

Calculated MW: 18 kDa; Observed MW: 23 kDa

 

Background

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

 

Research Area

Cell Biology

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