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Bcl-XL Rabbit Monoclonal Antibody

Bcl-XL Rabbit Monoclonal Antibody

Cat: AMRe83686
Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC/IF,ICC,FC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Bcl-XL Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

Bcl-XL Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ICC,FC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

Bcl-XL

Alternative Names

Apoptosis regulator Bcl-X; BLC2L; Bcl-2-like 1 protein bclxl; BCL2L; BCL2L1; BCLX;;Bcl 2 L1

Gene ID

SwissProt ID

Q07817

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50

Molecular Weight

26 kDa

 

Background

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

 

Research Area

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