CD147 (8C17) Rabbit Monoclonal Antibody-EnkiLife

CD147 (8C17) Rabbit Monoclonal Antibody

Summary

Production Name	CD147 (8C17) Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,ICC/IF,IF-P
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification	Affinity purification

Immunogen

Gene Name	BSG
Alternative Names	5A11; 5F7; Basigin; Bsg; CD147; Collagenase stimulatory factor; EMMPRIN; M6 leukocyte activation antigen; Neurothelin; OK blood group antigen; TCSF; Tumor cell derived collagenase stimulatory factor;
Gene ID	682
SwissProt ID	P35613

Application

Dilution Ratio	WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,IF-P 1:50-1:200
Molecular Weight	42kDa

Background

Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). [Isoform 1]: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857).

Research Area

Immunology; Endothelial Cells; Neuroscience; Visual system; Microbiology; SARS Coronavirus; Carbohydrate metabolism; Neurogenesis; Cancer; Metabolism of carbohydrates; Cardiovascular; Endothelial Cell Markers